:root {
  --bg: #fbfdff;
  --paper: #fffefa;
  --surface: #ffffff;
  --surface-soft: #eef4fb;
  --line: #dbe6f0;
  --rule: rgba(83, 131, 195, 0.075);
  --text: #162333;
  --muted: #62758c;
  --navy: #2c4566;
  --main: #5383c3;
  --main-dark: #426899;
  --main-darker: #2c4566;
  --main-light: #588acc;
  --focus: #6eadff;
  --soft-blue: #7496c2;
  --pending: #9bacc2;
  --accent-warm: #c29253;
  --blue: #5383c3;
  --warning: #c29253;
  --shadow: 0 9px 20px rgba(44, 69, 102, 0.075);
  --radius: 8px;
  --max: 1120px;
}

* {
  box-sizing: border-box;
}

html {
  scroll-behavior: smooth;
  scrollbar-gutter: stable;
}

body {
  display: flex;
  min-height: 100vh;
  flex-direction: column;
  margin: 0;
  color: var(--text);
  background-color: var(--bg);
  background-image:
    linear-gradient(var(--rule) 1px, transparent 1px),
    linear-gradient(90deg, rgba(83, 131, 195, 0.045) 1px, transparent 1px);
  background-size: 30px 30px, 30px 30px;
  background-position: top center;
  font-family: "Yu Gothic UI", "Yu Gothic", "YuGothic", "Hiragino Sans", "Hiragino Kaku Gothic ProN", "Noto Sans JP", sans-serif;
  line-height: 1.8;
}

main {
  flex: 1;
}

img {
  display: block;
  max-width: 100%;
}

a {
  color: var(--main-dark);
  text-decoration: none;
}

a:hover {
  color: var(--main-darker);
  text-decoration: underline;
}

.skip-link {
  position: fixed;
  top: 8px;
  left: 8px;
  z-index: 100;
  padding: 10px 14px;
  border: 2px solid var(--main);
  border-radius: var(--radius);
  color: var(--main-darker);
  background: #fff;
  font-weight: 800;
  transform: translateY(-150%);
  transition: transform 120ms ease;
}

.skip-link:focus {
  color: var(--main-darker);
  text-decoration: none;
  transform: translateY(0);
}

a:focus-visible,
button:focus-visible,
input:focus-visible,
select:focus-visible,
[tabindex]:focus-visible {
  outline: 3px solid rgba(110, 173, 255, 0.65);
  outline-offset: 2px;
}

button,
select,
input,
textarea {
  font: inherit;
}

button {
  cursor: pointer;
}

.site-header {
  position: sticky;
  top: 0;
  z-index: 20;
  border-bottom: 1px solid rgba(83, 131, 195, 0.18);
  background: rgba(248, 251, 255, 0.94);
  backdrop-filter: blur(14px);
  box-shadow: 0 1px 10px rgba(44, 69, 102, 0.045);
}

.header-inner {
  display: flex;
  align-items: center;
  justify-content: space-between;
  max-width: var(--max);
  margin: 0 auto;
  padding: 12px 20px;
  gap: 16px;
}

.brand {
  display: inline-flex;
  align-items: center;
  gap: 0;
  color: var(--main-darker);
  font-weight: 800;
  letter-spacing: 0;
}

.nav-toggle {
  display: none;
  width: 44px;
  height: 44px;
  border: 1px solid rgba(83, 131, 195, 0.22);
  border-radius: var(--radius);
  color: var(--main-darker);
  background: rgba(255, 255, 255, 0.72);
  font-size: 22px;
}

.site-nav {
  display: flex;
  align-items: center;
  gap: 6px;
  flex-wrap: wrap;
  justify-content: flex-end;
}

.site-nav a {
  display: inline-flex;
  align-items: center;
  min-height: 44px;
  padding: 8px 10px;
  border-radius: var(--radius);
  color: var(--main-darker);
  font-size: 14px;
  line-height: 1.4;
  box-shadow: inset 0 0 0 0 transparent;
}

.site-nav a:hover,
.site-nav a.is-active {
  color: var(--main-darker);
  background: rgba(238, 246, 248, 0.95);
  box-shadow: inset 0 -2px 0 var(--main);
  text-decoration: none;
}

.hero {
  position: relative;
  min-height: 0;
  overflow: hidden;
  color: var(--text);
  background: transparent;
  border-bottom: 0;
}

.hero-inner {
  position: relative;
  width: min(100%, var(--max));
  margin: 0 auto;
  padding: 64px 20px 42px;
}

.eyebrow {
  margin: 0 0 12px;
  color: var(--main-dark);
  font-weight: 800;
  letter-spacing: 0;
}

.hero h1,
.page-hero h1 {
  margin: 0;
  max-width: 760px;
  font-size: clamp(30px, 4.6vw, 52px);
  line-height: 1.16;
  letter-spacing: 0;
}

.hero-copy,
.page-hero p {
  max-width: 1040px;
  margin: 18px 0 0;
  color: var(--muted);
  font-size: 18px;
}

.hero-actions,
.button-row {
  display: flex;
  gap: 12px;
  flex-wrap: wrap;
  margin-top: 22px;
}

.button {
  display: inline-flex;
  align-items: center;
  justify-content: center;
  min-height: 44px;
  padding: 9px 14px;
  border: 1px solid var(--line);
  border-radius: var(--radius);
  font-weight: 800;
  font-size: 14px;
  line-height: 1.4;
}

.button.primary {
  color: var(--main-darker);
  background: rgba(255, 255, 255, 0.78);
}

.button.secondary {
  color: var(--main-darker);
  border-color: #c8d9e7;
  background: rgba(233, 240, 247, 0.72);
}

.button.soft {
  color: var(--navy);
  background: var(--surface-soft);
}

.page-hero {
  color: var(--text);
  background: transparent;
  border-bottom: 0;
}

.page-hero .wrap {
  padding-top: 56px;
  padding-bottom: 28px;
}

.page-hero .labs-page-title {
  max-width: none;
  font-size: clamp(30px, 4.2vw, 50px);
  white-space: nowrap;
}

.wrap {
  width: min(100%, var(--max));
  margin: 0 auto;
  padding: 42px 20px;
}

.section-title {
  margin: 0 0 10px;
  color: var(--main-darker);
  font-size: clamp(23px, 3.4vw, 32px);
  line-height: 1.25;
  letter-spacing: 0;
}

.lead {
  max-width: 1040px;
  margin: 0 0 28px;
  color: var(--muted);
  font-size: 17px;
}

.grid {
  display: grid;
  gap: 34px 30px;
  padding-left: 0;
}

.grid.three {
  grid-template-columns: repeat(3, minmax(0, 1fr));
}

.grid.two {
  grid-template-columns: repeat(2, minmax(0, 1fr));
}

.grid.four {
  grid-template-columns: repeat(3, minmax(0, 1fr));
}

.grid.five {
  grid-template-columns: repeat(3, minmax(0, 1fr));
}

.card {
  position: relative;
  display: block;
  min-width: 0;
  overflow: visible;
  min-height: 210px;
  border: 1px solid rgba(83, 131, 195, 0.14);
  border-radius: 4px;
  color: inherit;
  background: linear-gradient(180deg, #eef8ff 0%, #e5f3ff 100%);
  box-shadow:
    0 2px 5px rgba(22, 35, 51, 0.05),
    0 8px 18px rgba(22, 35, 51, 0.08);
  transition: transform 180ms ease, border-color 180ms ease, background 180ms ease, box-shadow 180ms ease;
}

.card.pad {
  padding: 34px 28px 28px;
}

.card::before {
  content: "";
  position: absolute;
  top: -10px;
  left: 50%;
  width: 24%;
  min-width: 68px;
  max-width: 104px;
  height: 20px;
  border-radius: 3px;
  background: rgba(83, 131, 195, 0.18);
  box-shadow: 0 1px 2px rgba(22, 35, 51, 0.045);
  transform: translateX(-50%) rotate(-1.5deg);
  pointer-events: none;
  z-index: 2;
}

.card::after {
  content: none;
}

a.card:hover,
a.card:focus-visible {
  transform: translateY(-2px);
  border-color: rgba(83, 131, 195, 0.38);
  background: linear-gradient(180deg, #f3faff 0%, #e8f5ff 100%);
  box-shadow:
    0 4px 8px rgba(22, 35, 51, 0.06),
    0 12px 22px rgba(22, 35, 51, 0.1);
  text-decoration: none;
  outline: none;
}

a.card:focus-visible {
  box-shadow:
    0 0 0 3px rgba(110, 173, 255, 0.55),
    0 4px 8px rgba(22, 35, 51, 0.06),
    0 12px 22px rgba(22, 35, 51, 0.1);
}

.card-label {
  display: none;
  align-items: center;
  min-height: 26px;
  margin-bottom: 12px;
  padding: 3px 9px;
  border: 1px solid var(--label-border, rgba(44, 69, 102, 0.14));
  border-left: 4px solid var(--label-accent, var(--accent, var(--main)));
  border-radius: 3px;
  color: var(--main-darker);
  background: var(--label-bg, rgba(239, 245, 252, 0.92));
  box-shadow: 0 1px 2px rgba(44, 69, 102, 0.04);
  font-size: 12px;
  font-weight: 800;
}

.card.is-nursing {
  --accent: var(--main);
  --label-bg: #fbf5ea;
  --label-border: #e7d8bd;
}

.card.is-english {
  --accent: var(--main);
  --label-bg: #fbf5ea;
  --label-border: #e7d8bd;
}

.card.is-work {
  --accent: var(--soft-blue);
  --label-bg: #f0f5fb;
  --label-border: #d3dfec;
}

.card.is-log,
.card.is-template {
  --accent: var(--soft-blue);
  --label-bg: #f0f5fb;
  --label-border: #d3dfec;
}

.card.is-pending {
  --accent: var(--pending);
  --label-bg: #f1f4f6;
  --label-border: #d8e0e4;
}

.card.is-disease {
  --accent: var(--main);
  --label-accent: var(--main);
  --label-bg: #eef4fb;
  --label-border: #ccdced;
}

.card.is-medication {
  --accent: var(--main);
  --label-accent: var(--main);
  --label-bg: #eef4fb;
  --label-border: #ccdced;
}

.card.is-lab {
  --accent: var(--main);
  --label-accent: var(--main);
  --label-bg: #eef4fb;
  --label-border: #ccdced;
}

.card.is-skill {
  --accent: var(--main);
  --label-accent: var(--main);
  --label-bg: #eef4fb;
  --label-border: #ccdced;
}

.card h2,
.card h3 {
  margin: 0 0 14px;
  color: var(--main-darker);
  line-height: 1.35;
  letter-spacing: 0;
}

.card p {
  margin: 0 0 12px;
  color: var(--muted);
  line-height: 1.75;
}

/* Home page */
.home-hero {
  border-bottom: 1px solid rgba(83, 131, 195, 0.12);
}

.home-hero-layout {
  display: grid;
  grid-template-columns: minmax(0, 1fr) minmax(280px, 340px);
  align-items: center;
  gap: 52px;
  padding-top: 72px;
  padding-bottom: 64px;
}

.home-hero-content {
  min-width: 0;
}

.home-hero .eyebrow,
.section-kicker {
  color: var(--main-dark);
  font-size: 13px;
  font-weight: 900;
  letter-spacing: 0.08em;
}

.home-hero h1 {
  max-width: 720px;
  font-size: clamp(36px, 5vw, 58px);
  line-height: 1.22;
}

.home-hero .hero-copy {
  max-width: 720px;
}

.home-hero .button {
  min-height: 46px;
  padding: 10px 17px;
}

.home-hero .button.primary {
  border-color: var(--main-darker);
  color: #fff;
  background: var(--main-darker);
}

.home-hero .button.primary:hover,
.home-hero .button.primary:focus-visible {
  color: #fff;
  background: #213a5b;
  text-decoration: none;
}

.home-hero .button.secondary:hover,
.home-hero .button.secondary:focus-visible {
  text-decoration: none;
}

.hero-note {
  position: relative;
  padding: 34px 30px 28px;
  border: 1px solid rgba(194, 146, 83, 0.22);
  border-radius: 4px;
  background: linear-gradient(180deg, #fffdf2 0%, #fff9df 100%);
  box-shadow: var(--shadow);
  transform: rotate(0.7deg);
}

.hero-note::before {
  content: "";
  position: absolute;
  top: -11px;
  left: 50%;
  width: 92px;
  height: 21px;
  border-radius: 3px;
  background: rgba(83, 131, 195, 0.18);
  transform: translateX(-50%) rotate(-2deg);
}

.hero-note-title {
  margin: 0 0 14px;
  color: var(--main-darker);
  font-size: 18px;
  font-weight: 900;
}

.check-list {
  display: grid;
  gap: 10px;
  margin: 0;
  padding: 0;
  color: var(--muted);
  list-style: none;
}

.check-list li {
  position: relative;
  padding-left: 24px;
}

.check-list li::before {
  content: "✓";
  position: absolute;
  left: 0;
  color: var(--main-dark);
  font-weight: 900;
}

.home-section {
  padding-top: 58px;
  padding-bottom: 58px;
}

.home-first-section {
  padding-top: 64px;
}

.section-kicker {
  margin: 0 0 8px;
}

.home-feature-grid,
.home-topic-grid,
.home-link-grid {
  display: grid;
  padding: 0;
}

.home-feature-grid {
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 26px;
}

.home-topic-grid {
  grid-template-columns: repeat(4, minmax(0, 1fr));
  gap: 26px 20px;
}

.home-card {
  min-height: 0;
}

.home-feature-card.card.pad {
  display: flex;
  min-height: 230px;
  flex-direction: column;
  padding: 32px 26px 24px;
}

.home-feature-card p {
  flex: 1;
}

.card-number {
  display: block;
  margin-bottom: 8px;
  color: rgba(66, 104, 153, 0.65);
  font-size: 12px;
  font-weight: 900;
  letter-spacing: 0.12em;
}

.card-link,
.text-link {
  color: var(--main-dark);
  font-size: 14px;
  font-weight: 900;
}

.home-topic-card.card.pad {
  display: flex;
  min-height: 180px;
  flex-direction: column;
  padding: 28px 22px 20px;
}

.home-topic-card h3 {
  margin-bottom: 8px;
  font-size: 18px;
}

.home-topic-card p {
  flex: 1;
  margin-bottom: 10px;
  font-size: 14px;
  line-height: 1.65;
}

.home-topic-card .card-link {
  font-size: 12px;
}

.section-action {
  margin: 26px 0 0;
  text-align: right;
}

.home-link-grid {
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 14px;
  margin-top: 26px;
}

.home-link-panel {
  display: flex;
  min-height: 92px;
  align-items: center;
  justify-content: space-between;
  gap: 20px;
  padding: 18px 22px;
  border: 1px solid rgba(83, 131, 195, 0.16);
  border-left: 4px solid rgba(83, 131, 195, 0.5);
  border-radius: 4px;
  color: var(--text);
  background: rgba(255, 255, 255, 0.72);
  box-shadow: 0 3px 10px rgba(44, 69, 102, 0.05);
  transition: transform 180ms ease, border-color 180ms ease, box-shadow 180ms ease;
}

.home-link-panel:hover,
.home-link-panel:focus-visible {
  border-color: rgba(83, 131, 195, 0.42);
  color: var(--text);
  box-shadow: 0 7px 16px rgba(44, 69, 102, 0.09);
  transform: translateY(-2px);
  text-decoration: none;
}

.home-link-panel strong,
.home-link-panel small {
  display: block;
}

.home-link-panel strong {
  color: var(--main-darker);
}

.home-link-panel small {
  margin-top: 3px;
  color: var(--muted);
  font-size: 13px;
}

.home-about-section {
  padding-bottom: 74px;
}

.home-about-panel {
  display: grid;
  grid-template-columns: minmax(0, 1.4fr) minmax(280px, 0.8fr);
  gap: 44px;
  padding: 38px 40px;
  border: 1px solid rgba(83, 131, 195, 0.16);
  border-radius: 6px;
  background: rgba(255, 254, 250, 0.88);
  box-shadow: var(--shadow);
}

.home-about-panel p {
  margin: 12px 0 0;
  color: var(--muted);
}

.home-safety-note {
  align-self: center;
  padding-left: 28px;
  border-left: 1px dashed rgba(83, 131, 195, 0.3);
}

.home-safety-note strong {
  color: var(--main-darker);
}

.home-safety-note p {
  margin: 8px 0 12px;
  font-size: 14px;
}

.tag-list {
  display: flex;
  flex-wrap: wrap;
  gap: 8px;
  margin-top: 14px;
}

.tag {
  display: inline-flex;
  align-items: center;
  min-height: 30px;
  padding: 4px 9px;
  border: 1px solid var(--tag-border, #d7dde2);
  border-left: 4px solid var(--tag-accent, var(--main));
  border-radius: 3px;
  color: var(--main-darker);
  background: var(--tag-bg, #f4fbf9);
  font-size: 13px;
  font-weight: 700;
}

.tag-print {
  --tag-accent: var(--main);
  --tag-bg: #eef4fb;
  --tag-border: #ccdced;
}

.tag-training {
  --tag-accent: var(--main-dark);
  --tag-bg: #eef4fb;
  --tag-border: #ccdced;
}

.tag-general {
  --tag-accent: var(--accent-warm);
  --tag-bg: #fbf5e8;
  --tag-border: #e5d7b8;
}

.tag-pending {
  --tag-accent: var(--pending);
  --tag-bg: #f2f5f6;
  --tag-border: #d8e0e4;
}

.tag-blue {
  --tag-accent: var(--main);
  --tag-bg: #eef4fb;
  --tag-border: #ccdced;
}

.tag-pink {
  --tag-accent: var(--main-dark);
  --tag-bg: #eef4fb;
  --tag-border: #ccdced;
}

.tag-mint {
  --tag-accent: var(--main);
  --tag-bg: #eef4fb;
  --tag-border: #ccdced;
}

.tag-beige {
  --tag-accent: var(--accent-warm);
  --tag-bg: #fbf5e8;
  --tag-border: #e5d7b8;
}

.database-panel {
  border: 1px solid var(--line);
  border-radius: 6px;
  overflow: hidden;
  background: rgba(255, 255, 255, 0.84);
  box-shadow: 0 1px 2px rgba(18, 56, 95, 0.035);
}

.database-toolbar {
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 14px;
  padding: 14px;
  border-bottom: 1px solid var(--line);
  background: rgba(255, 254, 249, 0.92);
}

.database-controls {
  display: flex;
  gap: 10px;
  flex-wrap: wrap;
  justify-content: flex-end;
}

.database-toolbar input,
.database-toolbar select {
  width: min(100%, 360px);
  min-height: 44px;
  padding: 8px 10px;
  border: 1px solid var(--line);
  border-radius: 6px;
  color: var(--text);
  background: #fff;
  font: inherit;
}

.database-toolbar select {
  width: min(100%, 220px);
}

.database-table-wrap {
  overflow-x: auto;
}

.database-table {
  min-width: 900px;
  font-size: 14px;
}

.database-table th {
  white-space: nowrap;
}

.database-table th button {
  display: inline-flex;
  align-items: center;
  gap: 6px;
  width: 100%;
  padding: 0;
  border: 0;
  color: inherit;
  background: transparent;
  font: inherit;
  font-weight: 800;
  text-align: left;
  cursor: pointer;
}

.database-table th button span {
  min-width: 1em;
  color: var(--main);
  font-size: 11px;
}

.database-table td:first-child,
.database-table th:first-child {
  position: sticky;
  left: 0;
  z-index: 1;
  background: #fff;
}

.database-empty {
  padding: 20px;
  color: var(--muted);
}

.labs-toolbar {
  display: grid;
  grid-template-columns: 1fr;
  gap: 14px;
  padding: 14px;
}

.labs-toolbar strong {
  white-space: nowrap;
}

.labs-toolbar-heading {
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 12px;
}

.labs-reset {
  padding: 5px 10px;
  border: 1px solid var(--line);
  border-radius: 5px;
  color: var(--main-dark);
  background: #fff;
  font-size: 13px;
  font-weight: 800;
}

.labs-primary-controls {
  display: block;
}

.labs-static-summary {
  margin: 0 0 12px;
  color: var(--muted);
  font-size: 14px;
}

.labs-static-summary[hidden],
.labs-toolbar[hidden] {
  display: none;
}

.labs-primary-controls input {
  max-width: none;
}

.labs-column-filters {
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 10px;
  padding-top: 12px;
  border-top: 1px dashed rgba(83, 131, 195, 0.24);
}

.labs-column-filters label {
  display: grid;
  gap: 4px;
  min-width: 0;
}

.labs-column-filters label > span {
  color: var(--main-darker);
  font-size: 12px;
  font-weight: 800;
}

.labs-toolbar input,
.labs-toolbar select {
  width: 100%;
  min-width: 0;
  min-height: 44px;
  padding-block: 8px;
  font-size: 14px;
}

.labs-table {
  min-width: 850px;
  table-layout: fixed;
}

.labs-table th:first-child {
  position: static;
  background: #eef4fb;
}

.labs-table td:first-child {
  position: static;
  background: transparent;
}

.labs-table th:nth-child(1),
.labs-table td:nth-child(1) {
  width: 25%;
}

.labs-table th:nth-child(2),
.labs-table td:nth-child(2) {
  width: 14%;
}

.labs-table th:nth-child(3),
.labs-table td:nth-child(3) {
  width: 16%;
}

.labs-table th:nth-child(4),
.labs-table td:nth-child(4) {
  width: 30%;
}

.labs-table th:nth-child(5),
.labs-table td:nth-child(5) {
  width: 15%;
}

.labs-table tbody tr {
  cursor: pointer;
}

.labs-table tbody tr:hover,
.labs-table tbody tr:focus-visible {
  background: rgba(238, 246, 248, 0.75);
  outline: 2px solid rgba(110, 173, 255, 0.45);
  outline-offset: -2px;
}

.labs-table tbody tr:hover td,
.labs-table tbody tr:focus-visible td {
  background: rgba(238, 246, 248, 0.75);
}

.labs-table .lab-row td:first-child {
  box-shadow: inset 4px 0 0 var(--lab-accent, var(--line));
}

.lab-row.is-count {
  --lab-accent: #8b74bd;
}

.lab-row.is-coagulation {
  --lab-accent: #5f91c7;
}

.lab-row.is-chemistry {
  --lab-accent: #d77b72;
}

.lab-row.is-blood-gas {
  --lab-accent: #58a58f;
}

.lab-row.is-tumor-marker {
  --lab-accent: #c79846;
}

.lab-row.is-other {
  --lab-accent: #98a7b8;
}

.lab-category {
  display: inline-flex;
  align-items: center;
  min-height: 25px;
  padding: 3px 8px;
  border: 1px solid var(--category-border, #d5dde6);
  border-radius: 5px;
  color: var(--category-text, var(--main-darker));
  background: var(--category-bg, #f1f4f7);
  font-size: 12px;
  font-weight: 800;
  white-space: nowrap;
}

.lab-category.is-count {
  --category-bg: #f0ebfa;
  --category-border: #d8ccef;
  --category-text: #59447f;
}

.lab-category.is-coagulation {
  --category-bg: #e8f2fc;
  --category-border: #c6ddf3;
  --category-text: #315f8f;
}

.lab-category.is-chemistry {
  --category-bg: #fbe9e6;
  --category-border: #f0c9c3;
  --category-text: #94473f;
}

.lab-category.is-blood-gas {
  --category-bg: #e5f5ef;
  --category-border: #bfe2d6;
  --category-text: #2f7462;
}

.lab-category.is-tumor-marker {
  --category-bg: #fbf2df;
  --category-border: #ead4a4;
  --category-text: #805c1d;
}

.lab-category.is-other {
  --category-bg: #eef1f4;
  --category-border: #d5dce4;
  --category-text: #59697c;
}

.lab-reference-range {
  color: var(--text);
  font-weight: inherit;
}

.lab-factor-tag {
  --factor-border: #cbd3d9;
  --factor-bg: #edf0f2;
  --factor-text: #46515c;
  display: inline-flex;
  margin: 0 4px 5px 0;
  padding: 3px 8px;
  border: 1px solid var(--factor-border);
  border-radius: 4px;
  color: var(--factor-text);
  background: var(--factor-bg);
  font-size: 13px;
  line-height: 1.45;
}

.lab-factor-tag.factor-circulatory {
  --factor-border: #e6aaaa;
  --factor-bg: #fbe5e5;
  --factor-text: #8c3030;
}

.lab-factor-tag.factor-respiratory {
  --factor-border: #abc9e8;
  --factor-bg: #e5f0fb;
  --factor-text: #285f91;
}

.lab-factor-tag.factor-digestive {
  --factor-border: #e5bd91;
  --factor-bg: #faead9;
  --factor-text: #805022;
}

.lab-factor-tag.factor-renal {
  --factor-border: #a9d5dc;
  --factor-bg: #e2f2f4;
  --factor-text: #286b75;
}

.lab-factor-tag.factor-infection {
  --factor-border: #dfc85f;
  --factor-bg: #fff3bd;
  --factor-text: #6f5b09;
}

.lab-factor-tag.factor-mental {
  --factor-border: #c8afe1;
  --factor-bg: #eee5f7;
  --factor-text: #654188;
}

.lab-factor-tag.factor-metabolism {
  --factor-border: #abd0b2;
  --factor-bg: #e5f2e7;
  --factor-text: #376d42;
}

.lab-factor-tag.factor-tumor {
  --factor-border: #e3b3ca;
  --factor-bg: #f8e4ee;
  --factor-text: #8c4164;
}

.lab-factor-tag.factor-musculoskeletal {
  --factor-border: #ceb6a2;
  --factor-bg: #efe6de;
  --factor-text: #72513a;
}

.lab-factor-tag.factor-ophthalmic {
  --factor-border: #9fcfd2;
  --factor-bg: #e2f4f4;
  --factor-text: #286b70;
}

.lab-factor-tag.factor-dermatology {
  --factor-border: #deb5cc;
  --factor-bg: #f8e7f0;
  --factor-text: #81435f;
}

.lab-factor-tag.factor-lifestyle,
.lab-factor-tag.factor-other {
  --factor-border: #cbd3d9;
  --factor-bg: #edf0f2;
  --factor-text: #46515c;
}

.notice {
  margin: 0 0 18px;
  padding: 14px 16px;
  border-left: 4px solid var(--main);
  border-radius: var(--radius);
  color: var(--main-darker);
  background: rgba(238, 246, 248, 0.8);
  font-weight: 700;
}

.medication-comparison-link {
  display: grid;
  margin: 0 0 26px;
  padding: 20px 22px;
  border: 1px solid rgba(83, 131, 195, 0.24);
  border-left: 5px solid var(--main);
  border-radius: var(--radius);
  color: var(--text);
  background: linear-gradient(135deg, rgba(255, 254, 250, 0.96), rgba(238, 244, 251, 0.96));
  box-shadow: 0 4px 14px rgba(44, 69, 102, 0.06);
  gap: 3px;
  transition: transform 180ms ease, border-color 180ms ease, box-shadow 180ms ease;
}

.medication-comparison-link:hover,
.medication-comparison-link:focus-visible {
  border-color: rgba(83, 131, 195, 0.48);
  color: var(--text);
  box-shadow: 0 8px 20px rgba(44, 69, 102, 0.1);
  text-decoration: none;
  transform: translateY(-1px);
}

.medication-comparison-link-kicker {
  color: var(--main-dark);
  font-size: 12px;
  font-weight: 900;
  letter-spacing: 0.08em;
}

.medication-comparison-link strong {
  color: var(--main-darker);
  font-size: clamp(18px, 2.4vw, 23px);
  line-height: 1.45;
}

.medication-comparison-link > span:last-child {
  color: var(--muted);
  font-size: 14px;
}

/* Medication comparison page */
.comparison-hero .wrap {
  padding-bottom: 32px;
}

.comparison-hero h1 {
  margin-bottom: 8px;
}

.breadcrumb {
  display: flex;
  align-items: center;
  margin: 0 0 24px;
  color: var(--muted);
  font-size: 13px;
  line-height: 1.5;
  gap: 8px;
  flex-wrap: wrap;
}

.breadcrumb a {
  color: var(--main-dark);
}

.comparison-page {
  padding-top: 20px;
}

.comparison-disclaimer {
  margin-bottom: 30px;
  font-weight: 600;
}

.comparison-toc {
  margin: 0 0 52px;
  padding: 26px;
  border: 1px solid rgba(83, 131, 195, 0.2);
  border-radius: var(--radius);
  background: rgba(255, 254, 250, 0.94);
  box-shadow: var(--shadow);
}

.comparison-toc h2 {
  margin: 0 0 17px;
  color: var(--main-darker);
  font-size: 20px;
}

.comparison-toc-grid {
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 10px;
}

.comparison-toc-grid a {
  display: flex;
  align-items: center;
  min-height: 52px;
  padding: 10px 12px;
  border: 1px solid rgba(83, 131, 195, 0.17);
  border-radius: 6px;
  color: var(--main-darker);
  background: rgba(238, 244, 251, 0.72);
  font-size: 14px;
  font-weight: 800;
  line-height: 1.45;
  gap: 9px;
}

.comparison-toc-grid a:hover,
.comparison-toc-grid a:focus-visible {
  border-color: rgba(83, 131, 195, 0.42);
  background: #f3f8fd;
  text-decoration: none;
}

.comparison-toc-grid a span {
  color: var(--main);
  font-size: 12px;
  font-weight: 900;
}

.comparison-section {
  scroll-margin-top: 92px;
  margin: 0 0 64px;
}

.comparison-page {
  overflow-x: hidden;
}

.comparison-section-header {
  display: flex;
  align-items: center;
  margin: 0 0 16px;
  gap: 15px;
}

.comparison-section-header h2 {
  margin: 0;
  color: var(--main-darker);
  font-size: clamp(24px, 3.2vw, 34px);
  line-height: 1.3;
}

.comparison-section-header .section-kicker {
  margin: 0 0 2px;
}

.comparison-number {
  display: grid;
  width: 54px;
  height: 54px;
  flex: 0 0 54px;
  place-items: center;
  margin: 0;
  border: 1px solid rgba(83, 131, 195, 0.25);
  border-radius: 50%;
  color: var(--main-darker);
  background: #eef4fb;
  font-size: 16px;
  font-weight: 900;
}

.comparison-intro {
  max-width: 900px;
  margin: 0 0 24px;
  color: var(--muted);
  font-size: 16px;
}

.comparison-visual {
  margin: 0 0 24px;
  padding: 24px;
  border: 1px solid rgba(83, 131, 195, 0.2);
  border-radius: 8px;
  background:
    linear-gradient(rgba(83, 131, 195, 0.045) 1px, transparent 1px),
    linear-gradient(90deg, rgba(83, 131, 195, 0.035) 1px, transparent 1px),
    rgba(255, 254, 250, 0.96);
  background-size: 22px 22px;
  box-shadow: 0 5px 16px rgba(44, 69, 102, 0.06);
}

.comparison-visual figcaption {
  display: flex;
  align-items: baseline;
  justify-content: space-between;
  margin: 0 0 20px;
  gap: 14px;
}

.comparison-visual figcaption strong {
  color: var(--main-darker);
  font-size: 18px;
}

.comparison-visual figcaption span {
  color: var(--muted);
  font-size: 12px;
  text-align: right;
}

.visual-antibiotics {
  overflow: hidden;
}

.visual-node {
  display: grid;
  align-content: center;
  min-width: 0;
  min-height: 100px;
  padding: 16px;
  border: 1px solid var(--visual-border, #c7d9ee);
  border-top: 5px solid var(--visual-accent, var(--main));
  border-radius: 7px;
  color: var(--text);
  background: var(--visual-bg, #edf5fd);
  text-align: center;
  gap: 3px;
}

.visual-node strong {
  color: var(--main-darker);
  font-size: 16px;
  line-height: 1.4;
}

.visual-node small {
  color: var(--muted);
  font-size: 12px;
  line-height: 1.5;
}

.visual-node-label {
  color: var(--visual-text, var(--main-dark));
  font-size: 12px;
  font-weight: 900;
}

.visual-node.tone-blue {
  --visual-accent: #5383c3;
  --visual-border: #c7d9ee;
  --visual-bg: #edf5fd;
  --visual-text: #365f94;
}

.visual-node.tone-red {
  --visual-accent: #c96f74;
  --visual-border: #e7c3c6;
  --visual-bg: #fbeded;
  --visual-text: #91484d;
}

.visual-node.tone-yellow {
  --visual-accent: #c69b48;
  --visual-border: #e7d5ab;
  --visual-bg: #fff8e8;
  --visual-text: #815f1f;
}

.visual-node.tone-green {
  --visual-accent: #5f9b77;
  --visual-border: #c4dccd;
  --visual-bg: #edf7f0;
  --visual-text: #3d7352;
}

.visual-node.tone-purple {
  --visual-accent: #8a6cac;
  --visual-border: #d4c5e3;
  --visual-bg: #f5effa;
  --visual-text: #684988;
}

.visual-footer {
  margin: 18px 0 0;
  padding: 11px 13px;
  border-radius: 5px;
  color: var(--main-darker);
  background: rgba(238, 244, 251, 0.88);
  font-size: 12px;
  font-weight: 800;
  line-height: 1.65;
  text-align: center;
}

.visual-start {
  width: min(100%, 330px);
  margin: 0 auto 28px;
  padding: 12px 16px;
  border: 2px solid var(--main);
  border-radius: 999px;
  color: var(--main-darker);
  background: #fff;
  font-weight: 900;
  text-align: center;
}

.visual-branch-grid {
  position: relative;
  display: grid;
  grid-template-columns: repeat(4, minmax(0, 1fr));
  gap: 12px;
}

.visual-branch-grid::before {
  content: "";
  position: absolute;
  top: -17px;
  left: 12.5%;
  right: 12.5%;
  height: 1px;
  background: rgba(83, 131, 195, 0.5);
}

.visual-branch-grid .visual-node::before {
  content: "";
  position: absolute;
  top: -17px;
  left: 50%;
  width: 1px;
  height: 17px;
  background: rgba(83, 131, 195, 0.5);
}

.visual-branch-grid .visual-node {
  position: relative;
}

.antibiotic-path {
  display: grid;
  grid-template-columns: repeat(4, minmax(0, 1fr));
  align-items: stretch;
  gap: 12px;
}

.antibiotic-path .visual-node:nth-child(3),
.antibiotic-path .visual-node:nth-child(4) {
  min-height: 128px;
}

.antibiotic-decision {
  display: grid;
  grid-template-columns: repeat(4, minmax(0, 1fr));
  margin-top: 14px;
  gap: 8px;
}

.antibiotic-decision span,
.antibiotic-decision strong {
  display: grid;
  min-height: 48px;
  place-items: center;
  padding: 8px;
  border-radius: 5px;
  color: var(--main-darker);
  background: #eef4fb;
  font-size: 12px;
  line-height: 1.4;
  text-align: center;
}

.antibiotic-decision strong {
  color: #376d42;
  background: #e5f2e7;
}

.coagulation-flow {
  display: grid;
  grid-template-columns: minmax(0, 1fr) auto minmax(0, 1fr) auto minmax(0, 1fr);
  align-items: center;
  max-width: 760px;
  margin: 0 auto;
  gap: 12px;
}

.coagulation-step {
  display: grid;
  min-height: 78px;
  place-items: center;
  padding: 12px;
  border: 2px solid #7496c2;
  border-radius: 999px;
  color: var(--main-darker);
  background: #eef4fb;
  font-weight: 900;
  text-align: center;
}

.coagulation-step small {
  display: block;
  color: var(--muted);
  font-size: 11px;
}

.flow-arrow {
  color: var(--main);
  font-size: 24px;
  font-weight: 900;
}

.doac-targets {
  display: grid;
  grid-template-columns: 3fr 1fr;
  max-width: 760px;
  margin: 18px auto 0;
  gap: 14px;
}

.doac-target {
  display: flex;
  align-items: center;
  justify-content: center;
  min-width: 0;
  padding: 13px;
  border: 1px solid;
  border-radius: 6px;
  flex-wrap: wrap;
  gap: 6px;
}

.doac-target span {
  flex-basis: 100%;
  font-size: 11px;
  font-weight: 900;
  text-align: center;
}

.doac-target strong {
  padding: 4px 8px;
  border-radius: 999px;
  background: rgba(255, 255, 255, 0.78);
  font-size: 12px;
}

.target-xa {
  border-color: #c4dccd;
  color: #376d42;
  background: #e5f2e7;
}

.target-thrombin {
  border-color: #d4c5e3;
  color: #654188;
  background: #eee5f7;
}

.hf-foundation {
  display: grid;
  grid-template-columns: repeat(4, minmax(0, 1fr));
  gap: 12px;
}

.hf-center {
  width: min(100%, 360px);
  margin: 15px auto;
  padding: 10px 15px;
  border-radius: 999px;
  color: #fff;
  background: var(--main-darker);
  font-size: 13px;
  font-weight: 900;
  text-align: center;
}

.hf-support {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  max-width: 760px;
  margin: 0 auto;
  gap: 12px;
}

.hf-support > div {
  display: grid;
  padding: 14px;
  border: 1px dashed rgba(83, 131, 195, 0.45);
  border-radius: 6px;
  background: rgba(255, 255, 255, 0.82);
  text-align: center;
}

.hf-support span,
.hf-support small {
  color: var(--muted);
  font-size: 11px;
}

.hf-support strong {
  color: var(--main-darker);
}

.sleep-balance {
  display: grid;
  grid-template-columns: 1fr auto 1fr;
  align-items: center;
  max-width: 700px;
  margin: 0 auto 18px;
  gap: 12px;
}

.sleep-wake,
.sleep-rhythm {
  padding: 11px;
  border-radius: 999px;
  color: var(--main-darker);
  background: #eef4fb;
  font-size: 12px;
  font-weight: 900;
  text-align: center;
}

.sleep-center {
  display: grid;
  width: 72px;
  height: 72px;
  place-items: center;
  border: 2px solid #8a6cac;
  border-radius: 50%;
  color: #654188;
  background: #eee5f7;
  font-weight: 900;
}

.sleep-class-grid {
  display: grid;
  grid-template-columns: repeat(4, minmax(0, 1fr));
  gap: 12px;
}

.nephron-path {
  display: grid;
  grid-template-columns: minmax(0, 1fr) auto minmax(0, 1fr) auto minmax(0, 1fr) auto minmax(0, 1fr);
  align-items: center;
  gap: 9px;
}

.nephron-segment {
  display: grid;
  min-height: 112px;
  align-content: center;
  padding: 14px 10px;
  border: 1px solid var(--segment-border);
  border-bottom: 6px solid var(--segment-accent);
  border-radius: 7px;
  background: var(--segment-bg);
  text-align: center;
  gap: 5px;
}

.nephron-segment span {
  color: var(--muted);
  font-size: 11px;
  font-weight: 800;
}

.nephron-segment strong {
  color: var(--main-darker);
  font-size: 13px;
  line-height: 1.45;
}

.segment-proximal {
  --segment-border: #d4c5e3;
  --segment-accent: #8a6cac;
  --segment-bg: #f5effa;
}

.segment-loop {
  --segment-border: #c7d9ee;
  --segment-accent: #5383c3;
  --segment-bg: #edf5fd;
}

.segment-distal {
  --segment-border: #d4c5e3;
  --segment-accent: #8a6cac;
  --segment-bg: #f5effa;
}

.segment-collecting {
  --segment-border: #d4c5e3;
  --segment-accent: #8a6cac;
  --segment-bg: #f5effa;
}

.diuretic-key {
  display: flex;
  justify-content: center;
  margin-top: 15px;
  gap: 18px;
  flex-wrap: wrap;
}

.diuretic-key span {
  display: inline-flex;
  align-items: center;
  color: var(--muted);
  font-size: 11px;
  font-weight: 700;
  gap: 6px;
}

.diuretic-key i {
  width: 12px;
  height: 12px;
  border-radius: 50%;
}

.key-na {
  background: #5383c3;
}

.key-water {
  background: #8a6cac;
}

.comparison-table-section {
  margin: 24px 0;
  padding: 22px;
  border: 1px solid rgba(83, 131, 195, 0.2);
  border-radius: 8px;
  background: rgba(255, 254, 250, 0.96);
  box-shadow: 0 4px 12px rgba(44, 69, 102, 0.045);
}

.comparison-table-section h3 {
  margin: 0 0 8px;
  color: var(--main-darker);
  font-size: 20px;
}

.comparison-table-section > p {
  margin: 0 0 16px;
  color: var(--muted);
  font-size: 14px;
}

.comparison-table-scroll {
  width: 100%;
  min-width: 0;
  max-width: 100%;
  overflow: auto;
  border: 1px solid rgba(83, 131, 195, 0.2);
  border-radius: 6px;
  background: #fff;
  overscroll-behavior-inline: contain;
}

.comparison-data-table {
  min-width: 720px;
  margin: 0;
  font-size: 13px;
  line-height: 1.6;
}

.comparison-data-table th,
.comparison-data-table td {
  padding: 11px 12px;
  border-right: 1px solid rgba(83, 131, 195, 0.12);
}

.comparison-data-table thead th {
  background: #e9f1fa;
  white-space: nowrap;
}

.comparison-data-table tbody th {
  min-width: 9em;
  color: var(--main-darker);
  background: #f5f8fc;
}

.comparison-data-table tbody tr:last-child > * {
  border-bottom: 0;
}

.fluid-number-table {
  min-width: 900px;
}

.fluid-number-table td:nth-child(n + 3):nth-child(-n + 7) {
  white-space: nowrap;
  text-align: center;
}

.comparison-table-note {
  margin: 12px 0 0 !important;
  color: var(--muted);
  font-size: 12px !important;
  line-height: 1.7;
}

.medication-detail-link {
  color: var(--main-darker);
  font-weight: 900;
  text-decoration: underline;
  text-decoration-color: rgba(83, 131, 195, 0.48);
  text-decoration-thickness: 2px;
  text-underline-offset: 3px;
}

.medication-detail-link:hover,
.medication-detail-link:focus-visible {
  color: #315f9b;
  text-decoration-color: currentColor;
}

.antibiotic-spectrum-table {
  min-width: 760px;
  table-layout: fixed;
  margin: 0;
  font-size: 13px;
  text-align: center;
}

.antibiotic-spectrum-table th,
.antibiotic-spectrum-table td {
  padding: 11px 8px;
  border-right: 1px solid rgba(83, 131, 195, 0.14);
  text-align: center;
  vertical-align: middle;
}

.antibiotic-spectrum-table thead th {
  color: var(--main-darker);
  background: #e9f1fa;
}

.antibiotic-spectrum-table thead th:first-child,
.antibiotic-spectrum-table tbody th {
  width: 18%;
}

.antibiotic-spectrum-table tbody th {
  background: #f7f9fc;
  text-align: left;
}

.antibiotic-spectrum-table small {
  display: block;
  margin-top: 2px;
  color: var(--muted);
  font-size: 10px;
  font-weight: 700;
  line-height: 1.4;
}

.spectrum-mark {
  display: inline-grid;
  width: 31px;
  height: 31px;
  place-items: center;
  border-radius: 50%;
  font-size: 18px;
  font-weight: 900;
}

.spectrum-evidence-button {
  display: inline-grid;
  place-items: center;
  padding: 3px;
  border: 0;
  border-radius: 50%;
  background: transparent;
  cursor: pointer;
}

.spectrum-evidence-button:hover .spectrum-mark,
.spectrum-evidence-button:focus-visible .spectrum-mark {
  box-shadow: 0 0 0 3px #fff, 0 0 0 5px rgba(83, 131, 195, 0.55);
}

.spectrum-help {
  margin: 12px 0 0;
  color: var(--main-darker);
  font-size: 12px;
  font-weight: 800;
  text-align: center;
}

.spectrum-mark.is-common,
.spectrum-legend .is-common {
  color: #376d42;
  background: #dff0e5;
}

.spectrum-mark.is-conditional,
.spectrum-legend .is-conditional {
  color: #815f1f;
  background: #fff0c7;
}

.spectrum-mark.is-no,
.spectrum-legend .is-no {
  color: #7a8490;
  background: #edf0f3;
}

.spectrum-legend {
  display: flex;
  justify-content: center;
  margin-top: 13px;
  color: var(--muted);
  font-size: 11px;
  font-weight: 700;
  gap: 12px 18px;
  flex-wrap: wrap;
}

.spectrum-legend span {
  display: inline-flex;
  align-items: center;
  gap: 6px;
}

.spectrum-legend b {
  display: inline-grid;
  width: 23px;
  height: 23px;
  place-items: center;
  border-radius: 50%;
}

.antibiotic-exclusions {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  margin-top: 16px;
  gap: 10px;
}

.antibiotic-exclusions p {
  margin: 0;
  padding: 12px;
  border: 1px dashed rgba(138, 108, 172, 0.42);
  border-radius: 6px;
  color: var(--text);
  background: rgba(245, 239, 250, 0.86);
  font-size: 12px;
  line-height: 1.65;
}

.antibiotic-exclusions strong {
  display: block;
  color: #654188;
}

.spectrum-evidence-modal {
  position: fixed;
  z-index: 1200;
  inset: 0;
}

.spectrum-evidence-backdrop {
  position: absolute;
  inset: 0;
  background: rgba(22, 38, 58, 0.52);
}

.spectrum-evidence-dialog {
  position: relative;
  z-index: 1;
  width: min(calc(100% - 32px), 560px);
  max-height: min(80vh, 620px);
  overflow-y: auto;
  margin: 10vh auto 0;
  padding: 28px;
  border: 1px solid rgba(83, 131, 195, 0.24);
  border-radius: 9px;
  background: #fffefa;
  box-shadow: 0 24px 70px rgba(22, 38, 58, 0.24);
}

.spectrum-evidence-dialog h3 {
  margin: 0 42px 12px 0;
  color: var(--main-darker);
  font-size: 20px;
}

.spectrum-evidence-dialog > p:not(.section-kicker) {
  margin: 0 0 18px;
  color: var(--text);
  line-height: 1.8;
}

.spectrum-evidence-dialog > a {
  color: var(--main-darker);
  font-weight: 900;
  text-decoration: underline;
  text-decoration-thickness: 2px;
  text-underline-offset: 3px;
}

.spectrum-evidence-close {
  position: absolute;
  top: 14px;
  right: 14px;
  display: grid;
  width: 36px;
  height: 36px;
  place-items: center;
  padding: 0;
  border: 1px solid rgba(83, 131, 195, 0.25);
  border-radius: 50%;
  color: var(--main-darker);
  background: #fff;
  font-size: 22px;
  cursor: pointer;
}

body.is-spectrum-evidence-open {
  overflow: hidden;
}

.visually-hidden {
  position: absolute !important;
  width: 1px !important;
  height: 1px !important;
  overflow: hidden !important;
  clip: rect(0 0 0 0) !important;
  white-space: nowrap !important;
}

.comparison-card-grid {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 18px;
}

.comparison-text-section {
  margin: 28px 0;
}

.comparison-text-section > h3 {
  margin: 0 0 8px;
  color: var(--main-darker);
  font-size: 20px;
}

.comparison-text-list {
  display: grid;
  grid-template-columns: minmax(0, 1fr);
}

.comparison-text-item {
  padding: 16px 0;
  border-bottom: 1px solid rgba(83, 131, 195, 0.18);
}

.comparison-text-item h3,
.comparison-text-item h4 {
  margin: 0 0 5px;
  color: var(--main-darker);
  font-size: 17px;
  line-height: 1.45;
}

.comparison-text-item p {
  margin: 0;
  color: var(--text);
  font-size: 14px;
  line-height: 1.8;
}

.comparison-text-item .comparison-examples {
  min-height: 0;
  margin: 0 0 5px;
  color: var(--muted);
  font-size: 13px;
  font-weight: 500;
}

.comparison-card {
  position: relative;
  min-width: 0;
  overflow: hidden;
  padding: 22px;
  border: 1px solid var(--comparison-border, #ccdaeb);
  border-top: 5px solid var(--comparison-accent, var(--main));
  border-radius: 7px;
  background: linear-gradient(145deg, #fffefa, var(--comparison-bg, #f1f6fc));
  box-shadow: 0 4px 12px rgba(44, 69, 102, 0.055);
}

.comparison-card h3 {
  margin: 0 0 4px;
  color: var(--main-darker);
  font-size: 19px;
  line-height: 1.4;
}

.comparison-examples {
  min-height: 1.5em;
  margin: 0 0 14px;
  color: var(--comparison-text, var(--main-dark));
  font-size: 13px;
  font-weight: 800;
}

.comparison-card dl {
  margin: 0;
}

.comparison-card dl > div {
  display: grid;
  grid-template-columns: 4.3em minmax(0, 1fr);
  padding: 10px 0;
  border-top: 1px dashed rgba(83, 131, 195, 0.18);
  gap: 10px;
}

.comparison-card dt {
  color: var(--comparison-text, var(--main-dark));
  font-size: 13px;
  font-weight: 900;
}

.comparison-card dd {
  margin: 0;
  color: var(--text);
  font-size: 14px;
  line-height: 1.75;
}

.comparison-card.tone-blue {
  --comparison-accent: #5383c3;
  --comparison-border: #c7d9ee;
  --comparison-bg: #edf5fd;
  --comparison-text: #365f94;
}

.comparison-card.tone-red {
  --comparison-accent: #c96f74;
  --comparison-border: #e7c3c6;
  --comparison-bg: #fbeded;
  --comparison-text: #91484d;
}

.comparison-card.tone-yellow {
  --comparison-accent: #c69b48;
  --comparison-border: #e7d5ab;
  --comparison-bg: #fff8e8;
  --comparison-text: #815f1f;
}

.comparison-card.tone-green {
  --comparison-accent: #5f9b77;
  --comparison-border: #c4dccd;
  --comparison-bg: #edf7f0;
  --comparison-text: #3d7352;
}

.comparison-card.tone-purple {
  --comparison-accent: #8a6cac;
  --comparison-border: #d4c5e3;
  --comparison-bg: #f5effa;
  --comparison-text: #684988;
}

.comparison-card.tone-gray {
  --comparison-accent: #8291a2;
  --comparison-border: #d1d8df;
  --comparison-bg: #f2f4f6;
  --comparison-text: #596878;
}

.comparison-caution {
  margin: 20px 0 0;
  padding: 17px 19px;
  border: 1px solid #e7d5ab;
  border-left: 5px solid #c69b48;
  border-radius: 6px;
  background: rgba(255, 248, 232, 0.85);
}

.comparison-caution strong {
  color: #76581e;
}

.comparison-caution p {
  margin: 4px 0 0;
  color: var(--text);
  font-size: 14px;
}

.comparison-sources {
  margin: 20px 0 0;
  padding: 18px 20px;
  border: 1px solid rgba(83, 131, 195, 0.17);
  border-radius: 6px;
  background: rgba(255, 255, 255, 0.66);
}

.comparison-sources h3 {
  margin: 0 0 8px;
  color: var(--main-darker);
  font-size: 15px;
}

.comparison-sources ul {
  margin: 0;
  padding-left: 1.3em;
  columns: 2;
  column-gap: 32px;
}

.comparison-sources li {
  margin: 0 0 6px;
  break-inside: avoid;
  color: var(--muted);
  font-size: 13px;
  line-height: 1.65;
}

.comparison-sources a {
  overflow-wrap: anywhere;
  text-decoration: underline;
  text-decoration-color: rgba(83, 131, 195, 0.4);
  text-underline-offset: 3px;
}

.comparison-review {
  margin: 8px 0 24px;
  padding: 18px 20px;
  border-top: 1px solid rgba(83, 131, 195, 0.25);
  border-bottom: 1px solid rgba(83, 131, 195, 0.25);
  color: var(--muted);
  font-size: 14px;
}

.comparison-review p {
  margin: 3px 0;
}

.comparison-back {
  margin: 0;
}

.reference-source-note {
  margin: 0 0 22px;
  padding: 18px 20px;
  border: 1px solid rgba(83, 131, 195, 0.2);
  border-left: 5px solid var(--main);
  border-radius: 6px;
  color: var(--text);
  background: rgba(255, 254, 250, 0.9);
  box-shadow: 0 3px 12px rgba(44, 69, 102, 0.05);
}

.reference-source-note strong {
  color: var(--main-darker);
}

.reference-source-note p {
  margin: 5px 0 0;
}

.reference-source-note .reference-source-caution {
  color: var(--muted);
  font-size: 14px;
}

.labs-safety-panel {
  margin: 0 0 26px;
  padding: 22px;
  border: 1px solid rgba(88, 165, 143, 0.3);
  border-radius: 8px;
  background: linear-gradient(135deg, rgba(240, 248, 245, 0.96), rgba(255, 254, 250, 0.96));
  box-shadow: 0 4px 14px rgba(44, 69, 102, 0.06);
}

.labs-safety-heading {
  display: flex;
  align-items: flex-end;
  justify-content: space-between;
  margin-bottom: 16px;
  gap: 18px;
}

.labs-safety-heading .eyebrow,
.labs-safety-heading h2,
.labs-reviewed-date {
  margin: 0;
}

.labs-safety-heading h2 {
  color: var(--main-darker);
  font-size: 21px;
}

.labs-reviewed-date {
  display: grid;
  color: var(--muted);
  font-size: 12px;
  text-align: right;
}

.labs-reviewed-date time {
  color: var(--text);
  font-weight: 700;
}

.labs-safety-grid {
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 12px;
}

.labs-safety-grid article {
  padding: 15px 16px;
  border: 1px solid rgba(88, 165, 143, 0.2);
  border-radius: 6px;
  background: rgba(255, 255, 255, 0.72);
}

.labs-safety-grid h3 {
  margin: 0 0 6px;
  color: var(--main-darker);
  font-size: 16px;
}

.labs-safety-grid p,
.labs-source-policy {
  margin: 0;
  color: var(--muted);
  font-size: 14px;
  line-height: 1.7;
}

.labs-source-policy {
  margin-top: 14px;
  padding-top: 13px;
  border-top: 1px dashed rgba(88, 165, 143, 0.35);
}

.labs-category-guide {
  margin: 0 0 22px;
}

#labs-database {
  scroll-margin-top: 82px;
}

.labs-category-guide-heading {
  display: flex;
  align-items: baseline;
  justify-content: space-between;
  margin-bottom: 12px;
  gap: 16px;
}

.labs-category-guide-heading h2,
.labs-category-guide-heading p {
  margin: 0;
}

.labs-category-guide-heading h2 {
  color: var(--main-darker);
  font-size: 21px;
}

.labs-category-guide-heading p {
  color: var(--muted);
  font-size: 14px;
}

.labs-category-guide-grid {
  display: grid;
  grid-template-columns: repeat(4, minmax(0, 1fr));
  gap: 12px;
}

.labs-category-guide-card {
  --guide-accent: #98a7b8;
  --guide-border: #d5dce4;
  --guide-bg: #f5f7f8;
  display: grid;
  min-width: 0;
  min-height: 112px;
  align-content: start;
  padding: 15px 16px;
  border: 1px solid var(--guide-border);
  border-left: 5px solid var(--guide-accent);
  border-radius: 6px;
  color: var(--text);
  background: var(--guide-bg);
  box-shadow: 0 3px 10px rgba(44, 69, 102, 0.055);
  text-align: left;
  transition: transform 150ms ease, box-shadow 150ms ease;
  gap: 5px;
}

.labs-category-guide-card strong {
  color: var(--main-darker);
  font-size: 17px;
}

.labs-category-guide-card span {
  color: var(--muted);
  font-size: 13px;
  line-height: 1.6;
}

.labs-category-guide-card.is-count {
  --guide-accent: #8b74bd;
  --guide-border: #d8ccef;
  --guide-bg: #f7f3fc;
}

.labs-category-guide-card.is-coagulation {
  --guide-accent: #5f91c7;
  --guide-border: #c6ddf3;
  --guide-bg: #f1f7fd;
}

.labs-category-guide-card.is-chemistry {
  --guide-accent: #d77b72;
  --guide-border: #f0c9c3;
  --guide-bg: #fdf3f1;
}

.labs-category-guide-card.is-blood-gas {
  --guide-accent: #58a58f;
  --guide-border: #bfe2d6;
  --guide-bg: #f0f8f5;
}

.labs-category-guide-card:not(:disabled):hover,
.labs-category-guide-card[aria-pressed="true"] {
  transform: translateY(-2px);
  box-shadow: 0 7px 16px rgba(44, 69, 102, 0.11), inset 0 -3px 0 var(--guide-accent);
}

.labs-category-guide-card:disabled {
  cursor: default;
}

.medications-toolbar {
  align-items: center;
  justify-content: flex-start;
  gap: 14px;
  padding: 10px 12px;
}

.medications-toolbar strong {
  flex: 0 0 auto;
  white-space: nowrap;
}

.medications-toolbar .database-controls {
  flex: 1 1 auto;
  display: grid;
  grid-template-columns: minmax(220px, 1fr) minmax(150px, 210px) minmax(170px, 240px);
  gap: 10px;
  justify-content: stretch;
}

.medications-toolbar input,
.medications-toolbar select {
  width: 100%;
  min-height: 44px;
  padding-block: 8px;
  font-size: 14px;
}

.medications-sections {
  display: grid;
  gap: 34px;
  margin-top: 24px;
}

.medication-category {
  overflow: hidden;
  padding-top: 20px;
}

.medication-category h2 {
  margin: 0 0 12px;
  padding-inline: 14px;
  color: var(--main-darker);
  font-size: clamp(21px, 3vw, 28px);
  line-height: 1.3;
}

.medications-table {
  min-width: 980px;
  table-layout: fixed;
}

.medications-table th:first-child {
  position: static;
  background: #eef4fb;
}

.medications-table td:first-child {
  position: static;
  background: transparent;
}

.medications-table th:nth-child(1),
.medications-table td:nth-child(1) {
  width: 23%;
}

.medications-table th:nth-child(2),
.medications-table td:nth-child(2) {
  width: 27%;
}

.medications-table th:nth-child(3),
.medications-table td:nth-child(3) {
  width: 19%;
}

.medications-table th:nth-child(4),
.medications-table td:nth-child(4) {
  width: 31%;
}

.medication-name {
  display: block;
  color: var(--main-darker);
  font-weight: 800;
}

.medication-ingredient {
  display: block;
  margin-top: 4px;
  color: var(--muted);
  font-size: 0.86em;
  line-height: 1.45;
}

.medication-empty {
  color: var(--muted);
  font-size: 0.9em;
}

.medication-effect-list {
  display: flex;
  flex-wrap: wrap;
  align-items: flex-start;
  gap: 5px;
}

.medication-effect-tag {
  margin: 0;
  max-width: 100%;
  overflow-wrap: anywhere;
}

.database-hint {
  margin: 10px 2px 0;
  color: var(--muted);
  font-size: 14px;
}

.medications-table tbody tr {
  cursor: pointer;
}

.medications-table tbody tr:hover,
.medications-table tbody tr:focus-visible {
  background: rgba(238, 246, 248, 0.75);
  outline: 2px solid rgba(110, 173, 255, 0.45);
  outline-offset: -2px;
}

.medications-table tbody tr:hover td,
.medications-table tbody tr:focus-visible td {
  background: rgba(238, 246, 248, 0.75);
}

.modal[hidden] {
  display: none;
}

.modal {
  position: fixed;
  inset: 0;
  z-index: 50;
  display: grid;
  place-items: center;
  padding: 20px;
}

.modal-backdrop {
  position: absolute;
  inset: 0;
  background: rgba(22, 35, 51, 0.34);
}

.modal-dialog {
  position: relative;
  z-index: 1;
  width: min(100%, 640px);
  max-height: min(76vh, 720px);
  overflow: auto;
  padding: 26px;
  border: 1px solid rgba(83, 131, 195, 0.2);
  border-radius: var(--radius);
  background: rgba(248, 251, 255, 0.98);
  box-shadow: 0 18px 42px rgba(22, 35, 51, 0.18);
}

.modal-dialog h2 {
  margin: 0 0 18px;
  color: var(--main-darker);
}

.medication-modal .modal-dialog {
  width: min(100%, 760px);
}

.medication-modal-label {
  margin: 0 0 5px;
  color: var(--muted);
  font-size: 13px;
  font-weight: 800;
  letter-spacing: 0.08em;
}

.medication-modal .modal-dialog h2 {
  margin: 0 44px 4px 0;
}

.medication-modal-ingredient {
  margin: 0 0 22px;
  color: var(--muted);
}

.modal-close {
  position: absolute;
  top: 12px;
  right: 12px;
  display: grid;
  place-items: center;
  width: 36px;
  height: 36px;
  border: 1px solid rgba(83, 131, 195, 0.18);
  border-radius: 50%;
  color: var(--main-darker);
  background: #fff;
  font-size: 22px;
  line-height: 1;
  cursor: pointer;
}

.modal-details {
  display: grid;
  gap: 8px;
  margin: 0;
}

.modal-details dt {
  color: var(--main-darker);
  font-weight: 800;
}

.modal-details dd {
  margin: 0 0 16px;
  color: var(--text);
  overflow-wrap: anywhere;
  white-space: pre-wrap;
}

.modal-details dd a {
  color: var(--main-darker);
  font-weight: 700;
  text-decoration: underline;
  text-decoration-thickness: 1px;
  text-underline-offset: 3px;
}

body.is-modal-open {
  overflow: hidden;
}

.note-list {
  display: grid;
  gap: 12px;
  margin: 0;
  padding: 0;
  list-style: none;
}

.note-list li {
  padding-left: 18px;
  border-left: 4px solid var(--main);
}

.content {
  display: grid;
  grid-template-columns: minmax(0, 1fr) 280px;
  gap: 28px;
  align-items: start;
}

.article {
  border: 0;
  border-radius: 0;
  background: transparent;
  padding: 0;
}

.article h2 {
  margin-top: 34px;
  padding-top: 0;
  border-top: 0;
  color: var(--navy);
  line-height: 1.35;
}

.article h2:first-child {
  margin-top: 0;
  padding-top: 0;
  border-top: 0;
}

.article h3 {
  margin-top: 24px;
  color: var(--main-darker);
}

.article p,
.article li {
  color: var(--text);
}

.checklist {
  padding-left: 0;
  list-style: none;
}

.checklist li {
  position: relative;
  margin: 8px 0;
  padding-left: 30px;
}

.checklist li::before {
  content: "✓";
  position: absolute;
  left: 0;
  top: 0;
  display: grid;
  place-items: center;
  width: 22px;
  height: 22px;
  border-radius: 50%;
  color: #fff;
  background: var(--main);
  font-size: 13px;
  line-height: 1;
}

.sidebar {
  position: sticky;
  top: 86px;
  border: 1px solid var(--line);
  border-radius: var(--radius);
  background: var(--surface);
  padding: 18px;
}

.sidebar h2 {
  margin: 0 0 10px;
  color: var(--main-darker);
  font-size: 18px;
}

.sidebar a {
  display: block;
  padding: 7px 0;
  color: var(--muted);
}

.callout {
  margin: 22px 0;
  padding: 18px;
  border-left: 5px solid var(--blue);
  border-radius: var(--radius);
  background: #eef4fb;
}

.warning {
  border-left-color: var(--warning);
  background: #fff8ea;
}

.table-wrap {
  overflow-x: auto;
  border: 1px solid var(--line);
  border-radius: var(--radius);
}

table {
  width: 100%;
  border-collapse: collapse;
  background: #fff;
}

th,
td {
  padding: 12px;
  border-bottom: 1px solid var(--line);
  text-align: left;
  vertical-align: top;
}

th {
  color: var(--main-darker);
  background: #eef4fb;
}

.site-footer {
  margin-top: auto;
  border-top: 0;
  background: transparent;
}

.footer-inner {
  width: min(100%, var(--max));
  margin: 0 auto;
  padding: 28px 20px;
  color: var(--muted);
  font-size: 14px;
}

@media (prefers-reduced-motion: reduce) {
  html {
    scroll-behavior: auto;
  }

  *,
  *::before,
  *::after {
    scroll-behavior: auto !important;
    transition-duration: 0.01ms !important;
    animation-duration: 0.01ms !important;
    animation-iteration-count: 1 !important;
  }
}

@media (max-width: 900px) {
  .nav-toggle {
    display: inline-grid;
    place-items: center;
  }

  .site-nav {
    display: none;
    position: absolute;
    left: 16px;
    right: 16px;
    top: 66px;
    padding: 12px;
    border: 1px solid rgba(83, 131, 195, 0.18);
    border-radius: var(--radius);
    background: rgba(255, 255, 255, 0.97);
    box-shadow: 0 14px 28px rgba(44, 69, 102, 0.1);
  }

  .site-nav.is-open {
    display: grid;
    grid-template-columns: 1fr 1fr;
  }

  .site-nav a {
    padding: 10px;
    color: var(--text);
  }

  .site-nav a:hover,
  .site-nav a.is-active {
    color: var(--main-darker);
    background: rgba(238, 246, 248, 0.95);
    box-shadow: inset 3px 0 0 var(--main);
  }

  .labs-toolbar {
    align-items: stretch;
    grid-template-columns: 1fr;
  }

  .labs-toolbar .database-controls {
    grid-template-columns: 1fr;
  }

  .labs-column-filters {
    grid-template-columns: repeat(3, minmax(0, 1fr));
  }

  .labs-category-guide-grid {
    grid-template-columns: repeat(2, minmax(0, 1fr));
  }

  .medications-toolbar {
    align-items: stretch;
    flex-direction: column;
  }

  .medications-toolbar .database-controls {
    grid-template-columns: 1fr;
  }

  .comparison-toc-grid {
    grid-template-columns: repeat(2, minmax(0, 1fr));
  }

  .visual-branch-grid,
  .antibiotic-path,
  .hf-foundation,
  .sleep-class-grid {
    grid-template-columns: repeat(2, minmax(0, 1fr));
  }

  .visual-branch-grid::before,
  .visual-branch-grid .visual-node::before {
    content: none;
  }

  .antibiotic-decision {
    grid-template-columns: repeat(2, minmax(0, 1fr));
  }

  .nephron-path {
    grid-template-columns: repeat(2, minmax(0, 1fr));
  }

  .nephron-path .flow-arrow {
    display: none;
  }

  .comparison-sources ul {
    columns: 1;
  }

  .grid.three,
  .grid.four,
  .grid.five,
  .grid.two,
  .content {
    grid-template-columns: repeat(2, minmax(0, 1fr));
  }

  .sidebar {
    position: static;
  }

  .home-hero-layout {
    grid-template-columns: 1fr;
    gap: 42px;
  }

  .hero-note {
    max-width: 620px;
    transform: none;
  }

  .home-feature-grid {
    grid-template-columns: repeat(2, minmax(0, 1fr));
  }

  .home-topic-grid {
    grid-template-columns: repeat(2, minmax(0, 1fr));
  }

  .home-about-panel {
    grid-template-columns: 1fr;
    gap: 28px;
  }

  .home-safety-note {
    padding-top: 24px;
    padding-left: 0;
    border-top: 1px dashed rgba(83, 131, 195, 0.3);
    border-left: 0;
  }
}

@media (min-width: 901px) and (max-width: 1100px) {
  .grid.three,
  .grid.two,
  .grid.five,
  .grid.four {
    grid-template-columns: repeat(2, minmax(0, 1fr));
  }
}

@media (max-width: 620px) {
  .header-inner {
    padding-inline: 14px;
  }

  .brand {
    font-size: 14px;
  }

  .site-nav.is-open {
    grid-template-columns: 1fr;
  }

  .hero {
    min-height: 0;
  }

  .hero-inner,
  .page-hero .wrap,
  .wrap {
    padding-inline: 16px;
  }

  .article {
    padding: 20px;
  }

  .grid.three,
  .grid.four,
  .grid.five,
  .grid.two,
  .content {
    grid-template-columns: 1fr;
  }

  .card {
    min-height: 178px;
  }

  .card.pad {
    padding: 30px 24px 24px;
  }

  .card::before {
    left: 50%;
    width: 26%;
    min-width: 72px;
    height: 18px;
  }

  .hero-copy,
  .page-hero p {
    font-size: 16px;
  }

  .page-hero .labs-page-title {
    font-size: clamp(20px, 6.2vw, 34px);
    line-height: 1.25;
    white-space: normal;
  }

  .labs-page-title span {
    display: block;
    white-space: nowrap;
  }

  .home-hero-layout {
    gap: 38px;
    padding-top: 52px;
    padding-bottom: 50px;
  }

  .home-hero h1 {
    font-size: clamp(32px, 10vw, 42px);
  }

  .home-hero .hero-actions {
    align-items: stretch;
    flex-direction: column;
  }

  .home-hero .button {
    width: 100%;
  }

  .hero-note {
    padding: 32px 24px 24px;
  }

  .home-section,
  .home-first-section {
    padding-top: 46px;
    padding-bottom: 46px;
  }

  .home-feature-grid,
  .home-topic-grid,
  .home-link-grid {
    grid-template-columns: 1fr;
  }

  .home-feature-grid,
  .home-topic-grid {
    gap: 22px;
  }

  .home-feature-card.card.pad {
    min-height: 190px;
    padding: 30px 22px 22px;
  }

  .home-topic-card.card.pad {
    min-height: 150px;
    padding: 26px 20px 18px;
  }

  .section-action {
    text-align: left;
  }

  .home-link-panel {
    min-height: 82px;
    padding: 16px 18px;
  }

  .home-about-panel {
    padding: 28px 22px;
  }

  .medication-comparison-link {
    padding: 17px 18px;
  }

  .comparison-page {
    padding-top: 12px;
  }

  .comparison-toc {
    margin-bottom: 42px;
    padding: 20px 18px;
  }

  .comparison-toc-grid {
    grid-template-columns: 1fr;
  }

  .comparison-toc-grid a {
    min-height: 48px;
  }

  .comparison-section {
    margin-bottom: 54px;
    scroll-margin-top: 76px;
  }

  .comparison-section-header {
    align-items: flex-start;
    gap: 11px;
  }

  .comparison-number {
    width: 43px;
    height: 43px;
    flex-basis: 43px;
    font-size: 13px;
  }

  .comparison-section-header h2 {
    font-size: clamp(22px, 6.7vw, 28px);
  }

  .comparison-card-grid {
    grid-template-columns: 1fr;
    gap: 14px;
  }

  .comparison-text-list {
    grid-template-columns: 1fr;
  }

  .comparison-text-item {
    padding: 14px 0;
  }

  .comparison-card {
    padding: 18px 17px;
  }

  .comparison-table-section {
    padding: 18px 15px;
  }

  .comparison-table-section h3 {
    font-size: 18px;
  }

  .responsive-comparison-table {
    min-width: 0;
  }

  .responsive-comparison-table thead {
    position: absolute;
    width: 1px;
    height: 1px;
    overflow: hidden;
    clip: rect(0 0 0 0);
    white-space: nowrap;
  }

  .responsive-comparison-table,
  .responsive-comparison-table tbody,
  .responsive-comparison-table tr,
  .responsive-comparison-table th,
  .responsive-comparison-table td {
    display: block;
    width: 100%;
  }

  .responsive-comparison-table tbody tr {
    padding: 12px;
    border-bottom: 1px solid rgba(83, 131, 195, 0.2);
  }

  .responsive-comparison-table tbody tr:last-child {
    border-bottom: 0;
  }

  .responsive-comparison-table tbody th {
    min-width: 0;
    margin: -12px -12px 8px;
    width: calc(100% + 24px);
    padding: 9px 12px;
    border: 0;
    background: #e9f1fa;
  }

  .responsive-comparison-table tbody td {
    display: grid;
    grid-template-columns: minmax(7.2em, 38%) minmax(0, 1fr);
    padding: 7px 0;
    border: 0;
    gap: 10px;
  }

  .responsive-comparison-table tbody td::before {
    content: attr(data-label);
    color: var(--main-darker);
    font-size: 12px;
    font-weight: 900;
  }

  .fluid-number-table td:nth-child(n + 3):nth-child(-n + 7) {
    white-space: normal;
    text-align: left;
  }

  .antibiotic-exclusions {
    grid-template-columns: 1fr;
  }

  .comparison-visual {
    padding: 18px 16px;
  }

  .comparison-visual figcaption {
    align-items: flex-start;
    flex-direction: column;
    gap: 2px;
  }

  .comparison-visual figcaption span {
    text-align: left;
  }

  .visual-branch-grid,
  .antibiotic-path,
  .hf-foundation,
  .sleep-class-grid,
  .nephron-path {
    grid-template-columns: 1fr 1fr;
    gap: 9px;
  }

  .visual-node,
  .nephron-segment {
    min-height: 108px;
    padding: 13px 10px;
  }

  .visual-node strong {
    font-size: 14px;
  }

  .antibiotic-decision {
    grid-template-columns: 1fr 1fr;
  }

  .coagulation-flow {
    grid-template-columns: 1fr;
    gap: 4px;
  }

  .coagulation-flow .flow-arrow {
    font-size: 0;
    line-height: 1;
    text-align: center;
    transform: none;
  }

  .coagulation-flow .flow-arrow::before {
    content: "↓";
    font-size: 20px;
  }

  .coagulation-step {
    min-height: 58px;
  }

  .doac-targets {
    grid-template-columns: 1fr;
  }

  .hf-support {
    grid-template-columns: 1fr;
  }

  .sleep-balance {
    grid-template-columns: 1fr auto 1fr;
    gap: 6px;
  }

  .sleep-center {
    width: 58px;
    height: 58px;
  }

  .sleep-wake,
  .sleep-rhythm {
    padding: 9px 6px;
    font-size: 10px;
  }

  .diuretic-key {
    align-items: flex-start;
    flex-direction: column;
    gap: 5px;
  }

  .comparison-card dl > div {
    grid-template-columns: 3.8em minmax(0, 1fr);
    gap: 8px;
  }

  .comparison-sources {
    padding: 16px;
  }

  .labs-column-filters {
    grid-template-columns: repeat(2, minmax(0, 1fr));
  }

  .labs-table {
    width: auto;
    min-width: 760px;
    table-layout: auto;
    font-size: 13px;
  }

  .labs-table th,
  .labs-table td {
    padding: 9px 7px;
    white-space: nowrap;
  }

  .labs-table th button {
    gap: 3px;
  }

  .labs-table th button span {
    min-width: 0.75em;
  }

  .labs-table th:nth-child(n),
  .labs-table td:nth-child(n) {
    width: auto;
  }

  .labs-table .lab-category {
    min-height: 24px;
    padding: 3px 6px;
  }

  .labs-safety-panel {
    padding: 18px;
  }

  .labs-safety-heading {
    align-items: flex-start;
    flex-direction: column;
    gap: 8px;
  }

  .labs-reviewed-date {
    text-align: left;
  }

  .labs-safety-grid {
    grid-template-columns: 1fr;
  }

  .labs-category-guide-heading {
    align-items: flex-start;
    flex-direction: column;
    gap: 4px;
  }

  .labs-toolbar-heading {
    align-items: flex-start;
    flex-direction: column;
  }
}

@media print {
  :root {
    --text: #111;
    --muted: #333;
  }

  body {
    background: #fff;
    color: #111;
    font-size: 11pt;
    line-height: 1.55;
  }

  .site-header,
  .site-footer,
  .hero,
  .page-hero,
  .sidebar,
  .button-row,
  .hero-actions,
  .nav-toggle {
    display: none !important;
  }

  .wrap {
    width: 100%;
    padding: 0;
  }

  .content {
    display: block;
  }

  .article,
  .card {
    border: 0;
    box-shadow: none;
    padding: 0;
  }

  .article h2 {
    break-after: avoid;
    page-break-after: avoid;
  }

  a {
    color: #111;
    text-decoration: none;
  }

  .callout,
  .warning {
    border: 1px solid #bbb;
    background: #fff;
  }
}